ChromeMate®

Niacin bound Chromium

Chromium helps insulin metabolize fat, turn protein into muscle and convert sugar into energy. Chromium-activated insulin increases the amount of blood sugar available for energy production nearly twenty-fold. ChromeMate® is a unique, patented form of biologically active niacin-bound chromium called chromium nicotinate or polynicotinate that dramatically increases the effectiveness of chromium. Researchers have shown that ChromeMate's unique, patented oxygen-coordinated niacin-bound chromium complex is the safest and most potent form of chromium available as a dietary supplement. Rejuvenal chose it for its unique PhytoMatrix.

What is ChromeMate

ChromeMate® (generically called chromium nicotinate, chromium polynicotinate or niacin-bound chromium) is a patented oxygen-coordinated niacin-bound chromium complex that plays an important role in proper insulin function, maintenance of healthy blood sugar and cholesterol levels, normal energy production, and promotion of healthy body weight. Protected by three U.S. Patents, four international patents and other world-wide patents pending, ChromeMate® is the only niacin-bound chromium supplement with proven biological activity.

What does ChromeMate do?

Combined with exercise and a sensible diet, ChromeMate® helps:
• Maintain healthy body weight and promotes normal energy metabolism;
• Maintain healthy cholesterol levels and promotes cardiovascular health;
• Promote normal insulin function and maintains healthy blood sugar levels.
• Helps to increase lifespan of up to 20%


How does ChromeMate work?

Chromium is at the heart of a biologically active complex called Glucose Tolerance Factor or "GTF", which is responsible for potentiating (increasing) the action of insulin in the body. Insulin is a vital hormone responsible for transporting glucose inside cells and maintaining proper blood sugar and blood lipid (cholesterol) levels in the body. Chromium helps insulin metabolize fat, turn protein into muscle and convert sugar into energy. In fact, chromium-activated insulin increases the amount of blood sugar available for energy production nearly twenty-fold.
A lack of chromium can result in type II diabetes, obesity and heart disease. Dr. Walter Mertz, former director of the U.S. Department of Agriculture's Human Nutrition Research Center, established that GTF chromium consists of chromium bound to the B-vitamin, niacin. ChromeMate® is a unique form of oxygen-coordinated niacin-bound chromium found to be 18-times more potent than other forms of niacin-bound chromium tested. Protected by three U.S. patents, four international patents and other world-wide patents pending, ChromeMate® is the only niacin-bound chromium supplement with proven biological activity.


Comparing metabolic effects of six different commercial trivalent chromium compounds.

J Inorg Biochem. 2008 Jul 31.

Preuss HG, Echard B, Perricone NV, Bagchi D, Yasmin T, Stohs SJ.
Georgetown University Medical Center, Department of Physiology, Washington, DC 20057, United States.
Recent reports provide cogent evidence that the average individual becomes chromium deficient with age. Unfortunately, chromium deficiency is strongly associated with many aspects of the Metabolic Syndrome, including insulin resistance and type 2 diabetes. Since replacement of chromium, per os, often ameliorates many deleterious manifestations associated with insulin resistance and diabetes, it is not surprising that many different, commercial trivalent chromium compounds are available on the market. However, previous reports have shown that the form of trivalent chromium (negative charges) can influence effectiveness markedly.

We compared various commercial forms of trivalent chromium commonly used alone or in formulations, to examine whether they are equally effective and non-toxic. In the first study, five different chromium products were examined - citrate, amino acid chelate (AAC), chelavite, polynicotinate (NBC), and nicotinate. In the second study, effects of NBC and picolinate were assessed. Results demonstrated that only chelavite and NBC improved insulin sensitivity, and only NBC decreased systolic blood pressure (SBP) significantly.

In the second study, both picolinate and NBC significantly decreased SBP compared to control. NBC and picolinate decreased malonyldialdehyde concentrations (free radical formation) and DNA fragmentation in hepatic and renal tissues. No evidence of adverse effects was noted with any of the compounds tested.

In conclusion, while all the trivalent chromium compounds tested seem safe, only three enhanced insulin sensitivity (NBC, chelavite, and picolinate) and only two decreased SBP significantly (NBC and picolinate). Furthermore, both NBC and picolinate were protective in lessening free radical formation and DNA damage in the liver and kidneys.

ChromeMate

This ingredient is used in:

PhytoMatrix®

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Studies:

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