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Somatostatin
Growth Hormone Inhibiting Hormone
Somatostatin (also known as growth hormone inhibiting hormone (GHIH) or somatotropin release-inhibiting factor (SRIF)) is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.
Somatostatin has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids, the other of 28 amino acids.
Digestive system
Somatostatin is secreted in several locations in the digestive system:• stomach
• intestine
• delta cells of the pancreas
Studies:
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