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Skin build up, proteoglycans and photo aging.

Cartidea® is made from fish cartilage. It actually is hydrolized collagen type 2. It contains all nutrients which can be found in collagen type 2. It is a great ingredient to improve joint health and to help the skin to synthesize new proteoglycans and collagen type 2. Cartidea® contains about 30% chondroitin sulfate, 5% hyaluronic acid, 15% Glucosamin sulfate, 6,24% HydroxyProline and 8,95% Proline.

Cartidea® combined with vitamin C gives a beneficial effect on the formation of glucosaminoglycans and proteoglycans. Therefor it is highly effective in the improvement of skin quality and joint health.

Oral fish cartilage polysaccharides in the treatment of photoageing: biophysical findings.

Int J Cosmet Sci. 2002 Apr;24(2):81-7.

Distante F, Scalise F, Rona C, Bonfigli A, Fluhr JW, Berardesca E.
Institute for Skin Product Evaluation (ISPE), Milan, Italy.

The topically applied cosmetic products can be helpful in improving the aged skin condition. The present study shows how oral fish-cartilage (Cartidea®) food supplementation can be helpful in improving the treatment of ageing skin. A total of 30 healthy women with signs of skin ageing were studied.

Fifteen of the women were treated with a food supplement based on polysaccharides derived from the fish cartilage and a natural mix of antioxidants for 2 months and the other 15 with a placebo. Clinical evaluation and biophysical parameters related to skin function and wrinkle severity, such as silicone replica, skin thickness, mechanical properties, skin colour and capacitance, were measured. The results showed statistically significant changes in the active-treated group in comparison to the placebo. In particular, dermal thickness (treatment: from 1.13 to 1.23 mm; P < 0.001), skin wrinkling (treatment: from 9.5 to 3.5 R(a); P< 0.002), skin colour (treatment: brighter and less pigmented; P < 0.02) and viscoelasticity (treatment: from 0.70 to 0.97%; P < 0.02) showed considerable improvement. Most of these parameters are related to changes occurring within the dermal matrix, which is improved after the treatment, whereas most of the topically applied cosmetic products have a short-term effect on superficial structures. A combination treatment (oral and topical) can be more effective in reducing the signs of skin-ageing.